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Brochure (pdf) to find out more about F-MELT®
Long-nurtured inorganic synthesis technology for achieving rapid oral disintegration
F-MELT® is a spray-dried excipient used in orally disintegrating tablets that contain saccharides, disintegrating agent, and inorganic excipient. Orally disintegrating tablets can be easily manufactured through direct compression only by adding F-MELT® to the active ingredient and lubricant.
Characteristics of F-MELT®
| Characteristics | No. | Description |
|---|---|---|
| SD particles having both appropriate molding property and disintegrability | 1 | Orally disintegrating tablets can be conveniently manufactured by direct compression |
| 2 | F-MELT® possess good molding property that is well balanced with disintegrability. Its disintegration time is less than 30 seconds. | |
| 3 | Particles are spherical in shape, heavy, and have a high fluidity. | |
| Broad applicability | 4 | Customization is possible to meet customer needs. |
| Product tailored to global market | 5 | The pharmaceutical additives used in F-MELT® conform to pharmacopeias of major countries. (Patent acquired in Japan, India, and China, and filed in other overseas countries) |
| Easy to use and highly cost-effective | 6 | Since the pre-mix (basic design) is available, the time of drug development can be shortened. |
Orally disintegrating tablets can be manufactured through direct compression by mixing F-MELT® and an API. Addition of excipients, changing the lubricant or method of lubrication can overcome problems associated with tablet hardness and disintegration times.